The Effect of Eucaloric High-Protein Fiber Diet on Anthropometric and Metabolic Profile of Healthy Adults: A Repeated Single-Arm Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 13
- 试验地点
- 2
- 主要终点
- Fasting Plasma Glucose
研究概览
简要总结
The aims of this study is to investigate the effect of eucaloric high protein and fiber diet on healthy subjects.
详细描述
Several studies have shown that high protein diet can reduce body fat, increase muscle mass, and improve some metabolic parameters of subjects. Also, several studies have shown that high intake of fiber could reduce body weight and improve cardiometabolic parameters. Therefore, combining high-protein diet and high-fiber diet should have a positive synergistic effect on several of anthropometric and metabolic parameters. The aims of this study is to investigate the effect of eucaloric high protein and fiber diet on healthy subjects. Thirteen healthy subjects, age 29,85 ± 4,06 years old, with body mass index (BMI) 29,55 ± 4,12 kg/m2 were prescribed eucaloric high protein diet for two weeks, followed by washing period for two week. Then, they were prescribed with eucaloric high protein and high fiber diet for two more weeks. Twenty grams of dietary fiber were in the form of isomaltooligosaccharides (IMO) based creamer formulae. Their body composition, waist circumference, fasting blood glucose, blood uric acid and total cholesterol concentration were measured after every dietary intervention.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 50 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •(BMI) of >= 25.0
- •Healthy subjects
排除标准
- •pregnant,
- •under any medication
- •having any kind of diseases and acute infection
结局指标
主要结局
Fasting Plasma Glucose
时间窗: 2 weeks after meal
Fasting Plasma Glucose mmol/dl
body composition analysis (Arm-, Trunk-, Leg Fat composition)
时间窗: 2 weeks after meal
in Kg or %
Plasma Uric Acid
时间窗: 2 weeks after meal
Plasma Uric Acid mg/dl
Total Cholesterol
时间窗: 2 weeks after meal
Total Cholesterol Mg/dl
次要结局
未报告次要终点
研究者
Hendy Wijaya
Head of Clinical Pharmacology research laboratories
Universitas Katolik Widya Mandala Surabaya
