Dientamoeba fragilis: clinical symptoms, optimal treatment and molecular detectio
Completed
- Conditions
- 'Dientamoeba fragilis infection''parasitic gut-infection'10037072
- Registration Number
- NL-OMON39247
- Lead Sponsor
- Medisch Centrum Leeuwarden
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 500
Inclusion Criteria
- Subjects in between 0 and 18 years of age
- Positive PCR for Dientamoeba fragilis
Exclusion Criteria
- Contra-indication for the use of Metronidazole or Clioquinol
- Pregnancy
- Underlying disease or use of medication
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>To determine differences in efficacy of anti-protozoal treatment with<br /><br>clioquinol or metronidazole in children with symptomatic Dientamoeba fragilis<br /><br>infection. </p><br>
- Secondary Outcome Measures
Name Time Method <p>- To determine symptoms of Dientamoeba fragilis infection in children and adults<br /><br>- To assess duration of positivity of PCR after treatment<br /><br>- To determine incidence in non-symptomatic patients</p><br>