Neurophysiological Characterization of Postherniotomy Pain

Completed

• Conditions: Postoperative Pain; Postherniotomy Pain; Neuropathic Pain

• Registration Number: NCT00719368
• Lead Sponsor: Rigshospitalet, Denmark

Brief Summary

Sensory function is different in persistent postherniotomy pain patients than in operated controls, suggesting this to be a neuropathic pain syndrome. By performing quantitative sensory testing, the specific changes in pain patients will be revealed, thereby aiding in designing future treatment trials. MRI scans of the groin regions in pain patients and control patients will be evaluated by senior MRI specialists assessing potential pathology to the region (Mesh, inflammation, edema, funicle etc.) Assessors will be blinded to clinical status, and surgery.

Detailed Description

Not available

Study Timeline

• Study Start: 2006-01
• Study First Submitted: 2008-07-17
• Study First Submitted QC: 2008-07-18
• Study First Posted: 2008-07-21
• Primary Completion: 2012-09
• Study Completion: 2012-09
• Status Verified: 2012-10
• Last Update Submitted: 2014-04-04
• Last Update Posted: 2014-04-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

• Male patients >18 yrs
• Inguinal herniotomy >1 yr previously
• No sign of hernia recurrence
• Unilateral chronic groin pain lasting more than 3 months
• Moderate/severe pain related impairment of everyday activities.

Exclusion Criteria

• Other causes of persistent pain in groin region (hip, other surgical procedures)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sensory function	actual

Trial Locations

Locations (2)

Section for Surgical Pathophysiology; 🇩🇰 Copenhagen, Denmark

Danish Pain Research Centre; 🇩🇰 Aarhus, Denmark