Comparison of Post operative pain among men and women after a major surgery.

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2023/08/056142

Brief Summary

The study is to evaluate gender difference on pain perception in adults following major surgery under general anaesthesia. It is a prospective comparitive observational study with 64 participents(32 men and 32 women) in age group 18-65 belonging to ASA grade 1 and 2. Initially an epidural catheter will  be inserted in the desired space and test dose given, patient will then be induces under general anaesthesia. After completion of the surgery, patient will be extubated and pain will be recorded as per numerical pain rating scale, if >4 epidural analgesia with Inj 0.25% Bupivacaine given, pain severity will be assessed every 15 mins for first hour, every 30 minutes for next one hour and then two hourly for next 6 hours. Difference in pain perception and response to epidural analgesia among men and women noted and statistical analysis done.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2023-03-08
• Study Start: 2023-08-17

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 64

Inclusion Criteria

ASA 1 and 2 Patients posted for Elective Major Surgery under General Anaesthesia with Epidural Analgesia.

Exclusion Criteria

• Patients with chronic pain.
• Patients with Neurological disorders and Psychiatric diseases.
• Patients with coagulation defects.
• Patients with previous history of hypersensitivity reactions to local anaesthetics.
• Patients with obesity(BMI>30KG/M2).

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate gender difference on post operative pain perception in adults following major surgery under general anaesthesia	15 minutes, 30 minutes, 45 minutes, 1 hour, 1 hour 30 mins, 3 hours, 4 hours, 6 hours

Secondary Outcome Measures

Name	Time	Method
To evaluate gender difference in response to epidural analgesia.
To assess hemodynamic changes following epidural analgesia.	15 minutes, 30 minutes, 45 minutes, 1 hour, 1 hour 30 minutes,2 hours, 4 hours, 6 hours

Trial Locations

Locations (1)

Vardhman Mahavir Medical College and Safdarjang Hospital; 🇮🇳 Delhi, DELHI, India

Vardhman Mahavir Medical College and Safdarjang Hospital

🇮🇳Delhi, DELHI, India

Dr Aiswarya Vijay

Principal investigator

9894117683

aiswarya0410@gmail.com