Comparison of gender difference on post operative pain perception in adults following major surgery under General Anaesthesia
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 64
- 试验地点
- 1
- 主要终点
- To evaluate gender difference on post operative pain perception in adults following major surgery under general anaesthesia
研究概览
简要总结
The study is to evaluate gender difference on pain perception in adults following major surgery under general anaesthesia. It is a prospective comparitive observational study with 64 participents(32 men and 32 women) in age group 18-65 belonging to ASA grade 1 and 2. Initially an epidural catheter will be inserted in the desired space and test dose given, patient will then be induces under general anaesthesia. After completion of the surgery, patient will be extubated and pain will be recorded as per numerical pain rating scale, if >4 epidural analgesia with Inj 0.25% Bupivacaine given, pain severity will be assessed every 15 mins for first hour, every 30 minutes for next one hour and then two hourly for next 6 hours. Difference in pain perception and response to epidural analgesia among men and women noted and statistical analysis done.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA 1 and 2 Patients posted for Elective Major Surgery under General Anaesthesia with Epidural Analgesia.
排除标准
- •Patients with chronic pain.
- •Patients with Neurological disorders and Psychiatric diseases.
- •Patients with coagulation defects.
- •Patients with previous history of hypersensitivity reactions to local anaesthetics.
- •Patients with obesity(BMI>30KG/M2).
结局指标
主要结局
To evaluate gender difference on post operative pain perception in adults following major surgery under general anaesthesia
时间窗: 15 minutes, 30 minutes, 45 minutes, 1 hour, 1 hour 30 mins, 3 hours, 4 hours, 6 hours
次要结局
- To evaluate gender difference in response to epidural analgesia.
- To assess hemodynamic changes following epidural analgesia.(15 minutes, 30 minutes, 45 minutes, 1 hour, 1 hour 30 minutes,2 hours, 4 hours, 6 hours)