Assessment of Mandibular Osseous Changes Using Radiomorphometric Indices By Cone Beam Computed Tomography in Patients With End Stage Renal Failure Versus Normal Population
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Diagnosis
- Sponsor
- Cairo University
- Enrollment
- 26
- Primary Endpoint
- Mandibular cortical index(MCI)
- Last Updated
- 8 years ago
Overview
Brief Summary
This study will be observational study. The goal of this study is to evaluate the quality of mandible and to assess the correlation between the jaw bone quality in a sample of Egyptian patients with chronic renal failure and duration of dialysis using CBCT.
Detailed Description
This study will be observational study. The goal of this study is to evaluate the quality of mandible and to assess the correlation between the jaw bone quality in a sample of Egyptian patients with chronic renal failure and duration of dialysis using CBCT. Twenty-six subjects will be included in this study. These will comprise (13) CKD patients "the study group" and (13) healthy patients "the control group" recommended for CBCT imaging for implant placement. The control group will be selected from the Prosthodontic department and Oral Medicine department of Faculty of Oral and Dental Medicine, Cairo University, the study group will be selected from Nephrology and the artificial kidney unit El Kasr -Al Ain Hospital, Cairo University.
Investigators
Eman mamdouh
Assistant lecturer
Cairo University
Eligibility Criteria
Inclusion Criteria
- •End stage renal failure (in study group)
- •Undergone hemo-dialysis, three times/week (in study group)
- •Duration of dialysis (≥1 year) (in study group)
- •PTH (140-630)
- •Age group (18-40 years)
- •Free from any other systemic disease affecting the bone quality
- •Egyptian population
Exclusion Criteria
- •Early stage of renal disease
- •Patients with diabetes, hyperthyroidism, postmenopausal osteoporosis
- •Other language
- •Completely Edentulous patients.
Outcomes
Primary Outcomes
Mandibular cortical index(MCI)
Time Frame: Five months
Mandibular cortical index (MCI) is a qualitative index that determines the porosity degree of the lower cortical border of the mandible distal to the mental foramen.The lower border of the mandible can be classified into a three point scale according to MCI, C1: the cortex is sharp on both sides; C2: the cortex had semilunar defects(lacunar resorption) and c3: cortex is clearly porous
Secondary Outcomes
- Mental index(MI)(Five months)
- Panoramic mandibular index(PMI)(Fivemonths)
- Anti-gonial index(AI)(Five months)