NCT03975296已完成不适用
Transmuscular Quadratus Lumborum Block Versus Thoracic Paravertebral Block for Acute Pain and Quality of Recovery After Laparoscopic Partial Nephrectomy
Cui Xulei1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2019年6月10日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- cumulative morphine consumption
研究概览
简要总结
This trial is a prospective, randomized, single-center, open-label, parallel-arm, blinded-analysis trial, the objective of which is to evaluate the effect of transmuscular quadratus lumborum block (TMQLB) in the pain relief and quality of recovery in laparoscopic partial nephrectomy compared with thoracic paravertebral block (TPVB).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 17 Years 至 80 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18-70 yrs American Society of Anesthesiologists physical statusⅠ-Ⅲ Undergo laparoscopic nephrectomy Informed consent
排除标准
- •A known allergy to the drugs being used Coagulopathy, on anticoagulants Analgesics intake, history of substance abuse Participating in the investigation of another experimental agent Inability to properly describe postoperative pain to investigators (eg, language barrier, neuropsychiatric disorder)
研究组 & 干预措施
TMQLB group
Experimental
干预措施: preoperative single-shot TMQLB (Procedure)
TMQLB group
Experimental
干预措施: patient controlled intravenous analgesia(PCIA) (Drug)
TPVB group
Active Comparator
干预措施: preoperative single-shot TPVB (Procedure)
TPVB group
Active Comparator
干预措施: patient controlled intravenous analgesia(PCIA) (Drug)
结局指标
主要结局
cumulative morphine consumption
时间窗: within 48 postoperative hours
次要结局
- ambulation time(within the 5 days after surgery)
- nausea and vomiting episodes(within 24 hours after the surgery])
- time of recovery of bowl movement(within the 5 days after surgery)
- The pain scores determined by the numeric rating scale (NRS, 0-10)(within 48 postoperative hours)
- dermatomal distribution of sensory reduction(30 min after the block)
- quality of recovery evaluated by the self-assessment 15-item quality of recovery (QoR) scale(at 3 days and 5 days after the sugery)
- postoperative length of hospital stay(within 2 weeks after the surgery)
- patient satisfaction with anesthesia(48 hours after surgery)
研究者
Cui Xulei
The attending physician
Peking Union Medical College Hospital
研究点 (1)
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