Transmuscular Quadratus Lumborum Block Versus Thoracic Paravertebral Block for Acute Pain and Quality of Recovery After Laparoscopic Renal Surgery
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- mean VAS of the first postoperative 24 hours
研究概览
简要总结
This trial is a prospective, randomized, single-center, open-label, parallel-arm, blinded-analysis trial, the objective of which is to evaluate the effect of transmuscular quadratus lumborum block (TMQLB) in the pain relief and quality of recovery in laparoscopic renal surgery compared with thoracic paravertebral block (TPVB).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 17 Years 至 80 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •17~80 years of age;
- •American Society of Anesthesiologists physical status I-III;
- •undergoing laparoscopic nephrectomy.
排除标准
- •have a known allergy to the anesthetics being used;
- •infection at injection site
- •coagulopathy or history of anticoagulants use
- •chronic analgesics consumption or history of substance abuse
- •inability to properly describe postoperative pain or recovery to investigators (e.g., language barrier, neuropsychiatric disorder).
结局指标
主要结局
mean VAS of the first postoperative 24 hours
时间窗: within the first 24 postoperative hours
VAS is an internationally recognized pain scale with 11 points ranging from 0 to 10 points, with 0 defined as no pain and 10 defined as the worst pain imaginable. The VAS will be registered at 0, 2, 4, 8, 12, 24 hours after the surgery, and the primary outcome will be calculated as the mean VAS scores measured at these time point.
次要结局
- nausea score(at 0, 2, 4, 8, 12, 24 and 48 hours after the surgery;)
- pruritus score(at 0, 2, 4, 8, 12, 24 and 48 hours after the surgery;)
- postoperative length of hospital stay(after the surgery)
- quality of recovery evaluated by the self-assessment 15-item quality of recovery (QoR) scale(at 3 days and 5 days after the sugery)
- ambulation time(after the surgery)
- time of recovery of bowel movement(after the surgery)
- cumulative morphine consumption(at 0, 2,4, 8, 12, 24 ,48, 72hours and 7 day after the surgery)
- long-term pain control(at 48, 72 and 7 days after the surgery)
- dermatomal distribution of sensory loss(10, 20, 30 and 40 minutes after the intervention)
- patient satisfaction with anesthesia(at 48 hours after the surgery)
研究者
Cui Xulei
The attending physician
Peking Union Medical College Hospital