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Clinical Trials/ISRCTN21027481
ISRCTN21027481
Completed
未知

Goal-oriented cognitive Rehabilitation in Early-stage Alzheimer's disease: multi-centre single-blind randomised controlled Trial (GREAT)

Bangor University (UK)0 sites475 target enrollmentOctober 16, 2012
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ConditionsDementiaMental and Behavioural DisordersDementia in Alzheimer disease

Overview

Phase
未知
Intervention
Not specified
Conditions
Dementia
Sponsor
Bangor University (UK)
Enrollment
475
Status
Completed
Last Updated
3 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

2013 Protocol article in http://www.ncbi.nlm.nih.gov/pubmed/23710796 protocol 2019 Results article in https://www.ncbi.nlm.nih.gov/pubmed/30879470 2019 Results article in https://pubmed.ncbi.nlm.nih.gov/30724405/ (added 30/07/2021) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34702730/ (added 28/10/2021)

Registry
who.int
Start Date
October 16, 2012
End Date
January 31, 2017
Last Updated
3 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
Bangor University (UK)

Eligibility Criteria

Inclusion Criteria

  • •1\. The participant must have an ICD\-10 diagnosis of Alzheimer?s disease (AD), vascular dementia, or mixed AD and vascular dementia
  • •2\. The participant must be in the early stages of dementia, as indicated by an MMSE score of 18 or above
  • •3\. If taking acetylcholinesterase inhibitors, the participant must have been receiving a stable dose for one month prior to trial entry, and there should be no intention to change the dose over the period of participation in the study unless clinically indicated
  • •4\. The participant must have a carer who is willing to participate
  • •5\. The participant must be able to give informed consent

Exclusion Criteria

  • •1\. Participants will be excluded if they have a prior history of stroke, brain injury or other significant neurological condition
  • •2\. Participants will be excluded if they are unable to speak English

Outcomes

Primary Outcomes

Not specified

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