NCT03892408已完成不适用
High-flow Nasal Oxygen During Rigid Bronchoscopy Under General Anesthesia: a Randomized Controlled Trial
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 56
- 试验地点
- 1
- 主要终点
- the lowest oxygen saturation
研究概览
简要总结
The aim of this study is to evaluate the effect of high-flow nasal cannula oxygen administration on apnea in patients undergoing general anesthesia with rigid bronchoscopy compared with standard anesthesia methods.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
盲法说明
triple (Participant, Care Provider, investigator)
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •1. Patients undergoing general anesthesia with stent placement or bougination, biopsy or removal of a foreign body or a mass through a rigid bronchoscope
- •2. Patients aged 19 or older who meet American Society of Anesthesiologists (ASA) physical class 2-4
排除标准
- •1. Patients with dementia or cognitive impairment
- •2. pregnant women
- •3. Patients undergoing extracorporeal membrane oxygenation (ECMO)
- •4. Patients with active nasal bleeding), severe nasal obstruction, recent nasal trauma of surgery
- •5. Patients with current maxillofacial trauma or basal skull fracture
- •6. Patients who had previously undergone rigid bronchoscopy / surgery
- •7. If the subject includes a person who can not read the written consent (eg, illiterate, foreigner, etc.)
研究组 & 干预措施
Standard
No Intervention
standard anesthesia
Optiflow
Experimental
100 % of oxygen at 70 L / min through Optiflow ™ (Fisher and Paykel Healthcare Limited, Auckland, New Zealand)
干预措施: Optiflow ™ (Device)
结局指标
主要结局
the lowest oxygen saturation
时间窗: apnea period during the rigidbroscopic procedure/surgery
the lowest value of oxygen saturation measured percutaneously at extremity.
次要结局
- Hypoxia occurs the first time(intraoperative (The time taken to reach the point at which peripheral oxygen saturation fell below 90 for the first time immediately after the onset of apnea))
- End-tidal carbon dioxide partial pressure(Intraoperative (end-tidal CO2 partial pressure after 3 consecutive breaths after intubation or insertion of laryngeal mask following end of apnea))
- Arterial oxygen / carbon dioxide partial pressure(shortly after end of apnea (within 30 seconds))
- hypoxemia related surgical interruptions(4) hypoxemia related surgical interruptions during apneic period)
- Arterial oxygen / carbon dioxide partial pressure(shortly before start of apnea (within 30 seconds))
研究者
研究点 (1)
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