EUCTR2007-002341-20-GB
Active, not recruiting
Not Applicable
Randomized controlled trial comparing the effect of carbetocin vs syntocinon and ergometrine on postpartum haemorrhage in patients undergoing elective caesarean section - C.A.S.E. Trial
Queen Charlotte's and Chelsea Hospital0 sites600 target enrollmentMay 16, 2008
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Clinical efficacy comparing ( 2 drugs) carbetocin Vs syntocinon and ergometrine
- Sponsor
- Queen Charlotte's and Chelsea Hospital
- Enrollment
- 600
- Status
- Active, not recruiting
- Last Updated
- 10 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Full consent from patient, over 18 years of age
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
- •F.1\.2\.1 Number of subjects for this age range
- •F.1\.3 Elderly (\>\=65 years) no
- •F.1\.3\.1 Number of subjects for this age range
Exclusion Criteria
- •Hypersensitivity to carbetocin or oxytocin, hepatic or renal disease, vascular disease, severe cardiac disease, impaired pulmonary function, sepsis, severe hypertension, pre\-eclampsia or eclampsia, contraindications to ergometrine (previous hypersensitivity or idiosyncratic reactions to ergometrine or other ergot alkaloids, current use of doxycycline, tetracycline, sumatriptan, dopamine or methysergide, postpartum use of bromocriptine), general anaesthesia, Patients on erythromycin will be excluded as ergot toxicity can develop rapidly in patients on ergotamine.
Outcomes
Primary Outcomes
Not specified
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