Efficacy of Mefenamic Acid and Hyoscine for Pain Relief During Saline Infusion Sonohysterography in Infertile Women
- Registration Number
- NCT01060696
- Lead Sponsor
- Mahidol University
- Brief Summary
The infertility patients who are performed saline infusion sonohysterography (SIS) for studying the pathology inside the uterine cavity has pain. From pilot study the pain score is 6.80. It will have more benefits if we can manage this procedure with less or no pain. Many studies have tried to decrease pain such as types of catheter, intrauterine lidocaine infusion. Some have real effects but no study with oral Mefenamic acid or Hyoscine before the procedure.The drugs are safe and easy to administration and chief.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 138
Inclusion Criteria
- infertility female
- no history of HSG or Hysteroscopy
Exclusion Criteria
- vaginal or pelvic infection
- abnormal Pap smear
- contraindications for Mefenamic acid including upper and lower GI ulcers, bleeding disorder, Asthma or allergies, renal disease, using Warfarin,Aspirin, Lithium, history of Mefenamic acid or Hyoscine allergies
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- FACTORIAL
- Arm && Interventions
Group Intervention Description Hyoscine, Mefenamic acid, Placebo Mefenamic acid or Hyoscine or placebo Blind randomization to three groups. Mefenamic acid group Hyoscine group Placebo group
- Primary Outcome Measures
Name Time Method Pain relief by oral Mefenamic acid or Hyoscine and placebo during saline infusion sonohysterography Before, during and after the procedure
- Secondary Outcome Measures
Name Time Method Patients satisfaction during saline infusion sonohysterography After the procedure
Trial Locations
- Locations (1)
Siriraj hospital Mahidol university
🇹ðŸ‡Bangkok, Thailand