CPAP Boussignac Versus Bilevel Pressure Support Ventilation in Severe Acute Cardiogenic Pulmonary Edema

University Hospital, Rouen0 sitesNovember 1, 2002

ConditionsSevere Acute Cardiogenic Pulmonary Edema

Overview

Phase: Phase 3
Intervention: Not specified
Conditions: Severe Acute Cardiogenic Pulmonary Edema
Sponsor: University Hospital, Rouen
Primary Endpoint: Improvement in PaCO2 at the end of ventilation
Status: Completed
Last Updated: 16 days ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

To evaluate whether bilevel positive airway pressure more rapidly improves ventilation than continuous positive airway pressure (CPAP) in patients with acute pulmonary edema. CPAP is delivered via a simple device connected to oxygen.

Registry

clinicaltrials.gov

Start Date

November 1, 2002

End Date

December 28, 2005

Last Updated

16 days ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

University Hospital, Rouen

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•age \> 16 yrs, acute onset of severe respiratory distress, bilateral rales and typical findings of congestion on chest radiograph
•breathing frequency of \> 30/min, SpO2 \>90%, use of accessory respiratory muscles

Exclusion Criteria

Not provided

Outcomes

Primary Outcomes

Improvement in PaCO2 at the end of ventilation

Secondary Outcomes

Complications of each ventilation mode
Blood gases, vital signs
Time to transfer to medical ward
Time to hospital discharge
Easiness to use was evaluated by nurses
Patients operational tolerance
Endotracheal intubation, myocardial infarction and mortality during the first 24 hours
Duration of the ventilation