PROtein dose and Muscle Synthesis in critically ill patients (PROMS)

Not Applicable

Completed

• Conditions: Critical Illness; Intensive Care Nutrition; Diet and Nutrition - Other diet and nutrition disorders; Oral and Gastrointestinal - Normal oral and gastrointestinal development and function

• Registration Number: ACTRN12620000776909
• Lead Sponsor: Royal Adelaide Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-07-30
• Study Completion: 2022-10-28
• Last Update Posted: 16 January 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Inclusion:
*Adults (18 years of age and above)
*Admitted to the intensive care unit at the Royal Adelaide Hospital
*Mechanically ventilated and expected to remain ventilated until the day after recruitment
*Suitable for enteral feeding
*Arterial line in situ

Exclusion Criteria

Exclusions:
*Recent upper abdominal surgery
*Vegan
*Lactose intolerance
*Any order to withhold active treatment
*Jehovah’s Witness
*Pregnancy
*Receiving dialysis
*For muscle biopsy: Bleeding diathesis (INR > 2; APTT > 50, platelets < 50) including those receiving anticoagulants (other than low dose for DVT prophylaxis) and anti-platelet agents

Study & Design

• Study Type: Interventional
• Study Design: Not specified