Incidence and Risk Factors of Symptomatic Epidural Hematoma After Cervical Spine Surgery:a Retrospective Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 129
- 主要终点
- VAS(visual analogue pain scale)
研究概览
简要总结
The incidence and correlation of symptomatic epidural hematomas after cervical spine surgery was reviewed and analyzed, then it will provide reference to avoid the occurrence of this complication for the future clinical work.
详细描述
43 patients with symptomatic epidural hematoma after cervical spine surgery were enrolled in the Peking University Third hospital from January, 2009 to February, 2017. 86 patients without symptomatic epidural hematoma after cervical spine surgery during the same period were randomly selected as the control group. Demographic information (including gender, age, previous history, smoking history, etc.),disease parameters (diagnosis, mJOA(modified Japanese Orthopaedics association) score, NDI(neck disability index) score),laboratory and imaging parameters (including platelet, coagulation function, albumin, and OPLL),segments,treatment parameters (surgical method, number of surgical segments, operative time, intraoperative blood loss, anesthesia time, whether to use implants) and postoperative conditions (including the time of hematoma occurrence, diagnostic method, emergency debridement operation time, patient improvement before and after debridement) were collected.Firstly, risk factors for symptomatic epidural hematoma after cervical surgery were selected by univariate analysis,then independent risk factors were screened by multiple Logistic regression analysis.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with clinically and radiologically confirmed cervical spondylosis.
- •Cervical spine surgery was performed in our hospital
排除标准
- •Cervical trauma combined with fracture and dislocation.
- •Cervical cancer.
- •Cervical spine infection
- •Upper cervical spine surgery alone
结局指标
主要结局
VAS(visual analogue pain scale)
时间窗: 3 months after surgery
visual analogue pain scale, to evaluate patients' pain, form 0 to 10. more scores means more pain
Frankel score
时间窗: 3 months after surgery
Postoperative Neurological Function,From A to E. Score A means complete paralyzed and E means no paralyzed
mJOA
时间窗: 3 months after surgery
Postoperative Neurological Function, modified Japanese orthopaedics association, From 0 to 17 scores. More scores mean better recovery after surgery. Score 0 means the most severe symptoms.
次要结局
- the place that occur hematoma(From post operation immediately till 3 months after surgery)
- postoperative neurological recovery after treatment of hematoma(From post operation immediately till 3 months after surgery)
- whether patients need emergency debridement(From post operation immediately till 3 months after surgery)
- whether patients occur hematoma after surgery(From post operation immediately till 3 months after surgery)
