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临床试验/NCT05190276
NCT05190276已完成不适用

Incidence and Risk Factors of Symptomatic Epidural Hematoma After Cervical Spine Surgery:a Retrospective Study

Peking University Third Hospital0 个研究点目标入组 129 人开始时间: 2009年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
129
主要终点
VAS(visual analogue pain scale)

研究概览

简要总结

The incidence and correlation of symptomatic epidural hematomas after cervical spine surgery was reviewed and analyzed, then it will provide reference to avoid the occurrence of this complication for the future clinical work.

详细描述

43 patients with symptomatic epidural hematoma after cervical spine surgery were enrolled in the Peking University Third hospital from January, 2009 to February, 2017. 86 patients without symptomatic epidural hematoma after cervical spine surgery during the same period were randomly selected as the control group. Demographic information (including gender, age, previous history, smoking history, etc.),disease parameters (diagnosis, mJOA(modified Japanese Orthopaedics association) score, NDI(neck disability index) score),laboratory and imaging parameters (including platelet, coagulation function, albumin, and OPLL),segments,treatment parameters (surgical method, number of surgical segments, operative time, intraoperative blood loss, anesthesia time, whether to use implants) and postoperative conditions (including the time of hematoma occurrence, diagnostic method, emergency debridement operation time, patient improvement before and after debridement) were collected.Firstly, risk factors for symptomatic epidural hematoma after cervical surgery were selected by univariate analysis,then independent risk factors were screened by multiple Logistic regression analysis.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • Patients with clinically and radiologically confirmed cervical spondylosis.
  • Cervical spine surgery was performed in our hospital

排除标准

  • Cervical trauma combined with fracture and dislocation.
  • Cervical cancer.
  • Cervical spine infection
  • Upper cervical spine surgery alone

结局指标

主要结局

VAS(visual analogue pain scale)

时间窗: 3 months after surgery

visual analogue pain scale, to evaluate patients' pain, form 0 to 10. more scores means more pain

Frankel score

时间窗: 3 months after surgery

Postoperative Neurological Function,From A to E. Score A means complete paralyzed and E means no paralyzed

mJOA

时间窗: 3 months after surgery

Postoperative Neurological Function, modified Japanese orthopaedics association, From 0 to 17 scores. More scores mean better recovery after surgery. Score 0 means the most severe symptoms.

次要结局

  • the place that occur hematoma(From post operation immediately till 3 months after surgery)
  • postoperative neurological recovery after treatment of hematoma(From post operation immediately till 3 months after surgery)
  • whether patients need emergency debridement(From post operation immediately till 3 months after surgery)
  • whether patients occur hematoma after surgery(From post operation immediately till 3 months after surgery)

研究者

申办方类型
Other
责任方
Sponsor

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