Post-operative oxygen delivery in patients undergoing major non-cardiac surgery to reduce morbidity

Not Applicable

• Conditions: Surgery; Morbidity; Post-operative morbidity

• Registration Number: ISRCTN76894700
• Lead Sponsor: niversity College London Hospitals NHS Trust (UK)

Brief Summary

2015 Results article in http://www.ncbi.nlm.nih.gov/pubmed/25523407 results

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-03-15
• Study Completion: 2013-03-01
• Last Update Posted: 26 July 2021

Recruitment & Eligibility

• Sex: All
• Target Recruitment: 204

Inclusion Criteria

Patients undergoing major elective major surgical procedures that are associated with a high incidence of post-operative morbidity (abdominal/oesophageal/hepatic resection/gynaecology/urological reconstructive surgery) and who meet the following criteria:
1. American Society of Anaesthesiologists risk grade 3 - 4
2. Aged greater than 50 years, either sex
3. Greater than two risk factors defined by the Revised Cardiac Risk Index

Exclusion Criteria

1. Concurrent lithium therapy (incompatible with cardiac output monitoring device)
2. Acute myocardial ischaemia (contraindication for inotropic support)
3. Acute arrhythmias (contraindication for inotropic support)
4. Pregnancy (lithium-based cardiac output monitoring device)
5. Patients receiving palliative treatment only

Study & Design

• Study Type: Interventional
• Study Design: Not specified