Prospective Surveillance For Respiratory Virus Infections In Children Undergoing Hematopoietic Stem Cell Transplantation
Completed
- Conditions
- Respiratory Virus Infections
- Registration Number
- NCT00667303
- Lead Sponsor
- St. Jude Children's Research Hospital
- Brief Summary
The Study aims to prospectively survey the incidence of respiratory virus infections using molecular methodologies, in children undergoing hematopoietic stem cell transplantation
- Detailed Description
Samples will be collected with a nasopharyngeal wash and processed for direct fluorescent antibody, culture and Polymerase chain reaction (PCR)
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 51
Inclusion Criteria
- Age: Birth to 18 years.
- Patients undergoing an allogeneic HSCT for any disease.
- Parent or guardian willing to sign informed consent.
Exclusion Criteria
- Intra nasal lesion which precludes the performance of the nasopharyngeal wash.
- Patients on Continuous Positive Airway Pressure (CPAP) or Bilevel Positive Airway Pressure (BiPAP).
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of RV infection at any time after transplant: The day of onset of an infection is defined as the day when the first positive diagnostic test was performed. All patients will be followed until day +100 after the HSCT.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
St. Jude Children's Research Hospital
🇺🇸Memphis, Tennessee, United States
St. Jude Children's Research Hospital🇺🇸Memphis, Tennessee, United States