Early Left Atrial Septostomy Versus Conventional Approach after Venoarterial Extracorporeal Membrane Oxygenatio
- Conditions
- Symptoms, signs and abnormal clinical and laboratory findings, NEC
- Registration Number
- KCT0005955
- Lead Sponsor
- Chonnam National University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 116
1) Age more than 18 years old
2) Cardiogenic shock*
3) Successful VA-ECMO implantation
* The definition of cardiogenic shock
All these criteria should be met
1) Systolic blood pressure < 90 mmHg for 30 minutes, or needing inotropics or vasopressor to maintain systolic blood pressure > or = 90 mmHg
2) Pulmonary congestion on chest X-ray or increased left ventricular filling pressure by cardiac catheterization
3) At least one criteria of organ dysfunction
- mental obtundation, clammy ski, ogliuria, renal dysfunction, increased level of blood lactate
1) VA-ECMO after open heart surgery
2) VA-ECMO for the treatment of non-cardiac shock
3) Severe bleeding*
4) Terminal malignancy
5) Irreversible brain damage
6) Pregnancy or lactation
* The definition of severe bleeding
Hemoglobin decrease after VA-ECMO or cannulation site bleeding is not a exclusion criteria
1) Hypovolemic shock due to definite bleeding cause
2) Identifiable bleeding causes: gastrointestinal bleeding, hemothorax, traumatic bleeding, CNS hemorrhage, pulmonary hemorrhage
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cumulative incidence rate of all-cause death
- Secondary Outcome Measures
Name Time Method