Intravenous dexmedetomidine and paracetamol in bupivacaine spinal anesthesia
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2019/04/018801
- Lead Sponsor
- Department of Anaesthesia and Intensive Care
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1. American Society of Anesthesiologists (ASA) class I or II
2. Age: 18 to 70 years
3. Measuring 150-180 cm height, with body mass index (BMI) of 18-35 kg/m2
4. Patients undergoing elective lower abdominal and pelvic surgeries requiring spinal anaesthesia (maximum surgery duration-2hours)
1. All contraindications to spinal analgesia including bleeding diathesis, infection at the puncture site, spinal deformity, patient on anticoagulants, pre-existing neurological deficits in lower extremities, unwillingness to give consent.
2. Sensory blockade inadequate for surgery.
3. Patients on alpha-2 adrenergic receptors antagonists, calcium channel blockers, or angiotensin-converting enzyme inhibitors.
4. Patients having cardiac rhythm abnormalities.
5. History of alcoholism, drug abuse, and psychiatric disorders.
6. History of allergy to any of the study drugs.
7. Hepatic disease, renal disease, cardiopulmonary disease, hypertension,
diabetes, central or peripheral nervous system disorders.
8. Laparotomy, chronic abdominal pain undergoing treatment with opioid analgesic.
9. Pregnant patients.
10. Orthopaedic surgeries.
11. Surgeries extending more than 2 hours.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method