Novel Magnetic Resonance Imaging Techniques for Quantitative Cardiac Parametric Mapping

Medical University of South Carolina1 site in 1 country240 target enrollmentJune 20, 2014

ConditionsCardiomyopathy, Myocarditis, Ischemic Heart Disease

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Cardiomyopathy, Myocarditis, Ischemic Heart Disease
Sponsor: Medical University of South Carolina
Enrollment: 240
Locations: 1
Primary Endpoint: Clinical value of fast T1, T2, and T2* mapping of the left ventricle for the assessment of necrosis/scar, edema, and possible intramyocardial hemorrhage in patients with heart disease.
Status: Recruiting
Last Updated: 5 months ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The overall goal of this project is to evaluate the clinical potential of fast quantitative myocardial tissue characterization using recently emerged Cardiac Magnetic Resonance Imaging (CMR) techniques to aid the diagnosis, treatment, and follow up of patients with myocardial diseases, such as ischemic heart disease, cardiomyopathies, and myocarditis.

Registry

clinicaltrials.gov

Start Date

June 20, 2014

End Date

December 1, 2026

Last Updated

5 months ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

Medical University of South Carolina

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Subject must be 18-90 years of age.
•Subject must be previously diagnosed with or suspected to have one of the following conditions.
•Myocardial ischemia or infarction (group 1)
•Hypertrophic cardiomyopathy (group 2)
•Infiltrative cardiomyopathy (group 3)
•Myocarditis (group 4)
•Subject must have been referred for a clinically indicated CMR.

Exclusion Criteria

•Subject has any implanted device or condition in which an MR scan would be contraindicated.
•Subject has an acute psychiatric disorder or is cognitively impaired.
•Subject is using or is dependent on substances of abuse.
•Subject is unwilling to comply with the requirements of the protocol.
•Subject has previously entered this study.
•Subject has an allergy against MRI contrast agents.
•Subject is in acute unstable condition.

Outcomes

Primary Outcomes

Clinical value of fast T1, T2, and T2* mapping of the left ventricle for the assessment of necrosis/scar, edema, and possible intramyocardial hemorrhage in patients with heart disease.

Time Frame: 2 years