Quantitative Cardiac Parametric Mapping

Not Applicable

Recruiting

• Conditions: Cardiomyopathy, Myocarditis, Ischemic Heart Disease
• Interventions: Other: Cardiac Magnetic Resonance (CMR) imaging techniques

• Registration Number: NCT02855554
• Lead Sponsor: Medical University of South Carolina

Brief Summary

The overall goal of this project is to evaluate the clinical potential of fast quantitative myocardial tissue characterization using recently emerged Cardiac Magnetic Resonance Imaging (CMR) techniques to aid the diagnosis, treatment, and follow up of patients with myocardial diseases, such as ischemic heart disease, cardiomyopathies, and myocarditis.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2014-06-20
• Study First Submitted: 2016-07-28
• Study First Submitted QC: 2016-08-01
• Study First Posted: 2016-08-04
• Status Verified: 2024-11
• Last Update Submitted: 2024-11-07
• Last Update Posted: 2024-11-11
• Primary Completion: 2025-12
• Study Completion: 2025-12

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 240

Inclusion Criteria

• Subject must be 18-90 years of age.
• Subject must be previously diagnosed with or suspected to have one of the following conditions.
• Myocardial ischemia or infarction (group 1)
• Hypertrophic cardiomyopathy (group 2)
• Infiltrative cardiomyopathy (group 3)
• Myocarditis (group 4)
• Subject must have been referred for a clinically indicated CMR.

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Exclusion Criteria

• Subject has any implanted device or condition in which an MR scan would be contraindicated.
• Subject has an acute psychiatric disorder or is cognitively impaired.
• Subject is using or is dependent on substances of abuse.
• Subject is unwilling to comply with the requirements of the protocol.
• Subject has previously entered this study.
• Subject has an allergy against MRI contrast agents.
• Subject is in acute unstable condition.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Additional 5 minute research MR scan of heart.	Cardiac Magnetic Resonance (CMR) imaging techniques	The purpose of this is to evaluate new, faster MR scans

Primary Outcome Measures

Name	Time	Method
Clinical value of fast T1, T2, and T2* mapping of the left ventricle for the assessment of necrosis/scar, edema, and possible intramyocardial hemorrhage in patients with heart disease.	2 years

Trial Locations

Locations (1)

Medical University of South Carolina; 🇺🇸 Charleston, South Carolina, United States