跳至主要内容
临床试验/NCT03737552
NCT03737552已完成不适用

Sleep Patterns in Children and Adolescents With ADHD: Impact on Cognitive Functions and Quality of Life

Assiut University1 个研究点 分布在 1 个国家目标入组 84 人开始时间: 2019年4月23日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
84
试验地点
1
主要终点
polysomnography to measure total sleep time(minutes) in ADHD patients

研究概览

简要总结

This study is aimed to find out Sleep profile differences in children and adolescents with and without ADHD,Relationship between sleep profile disturbance and ADHD symptoms, Impact of sleep disturbance on cognition functions and quality of life.

详细描述

Attention deficit hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder of childhood, affecting 3 -5% children & adolescent worldwide . Inattention, hyperactivity, and impulsiveness are the major ADHD symptoms based on the diagnostic criteria of Diagnostic and Statistical Manual of Mental Disorders (DSM), Fifth Edition .

Sleep has been referred to as a "window to the central nervous system", owing to its close associations with many other neurophysiological variables. Children are highly vulnerable to sleep disruptions in early childhood, perhaps due to the complexity of the sleep process and children's reliance on caregivers for achieving and maintaining sleep .

The relationship between sleep and ADHD is a complex process and has gained renewed interest since clinicians and researchers observed that sleep-related problems and complaints are relatively common among children with ADHD .Previous studies have shown that About 25-50% of children and adolescents with ADHD have sleep disorders , including nocturnal awakenings, phase delay, increased night time activity and insomnia.

Evaluation of sleep problems in child &adolescent clinical settings is commonly lacking, often unrecognized and go untreated in clinical setting. So, Untreated sleep disturbances and sleep disorders pose significant adverse daytime consequences and place children at considerable risk for poor health outcomes . Sleep disturbances impair a child's cognitive functioning and contribute to problems with school attendance and performance .

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
6 Years 至 17 Years(Child)
性别
All
接受健康志愿者
是

入选标准

  • •Ages 6-17 years inclusive
  • •males or females
  • •Intelligence Quotient( IQ) > or equal 80 detected by Wechsler Intelligence Scale for Children .
  • •Willingness to comply with all study requirements
  • •Inclusion criteria for ADHD group only:
  • •confirmed newly diagnosed ADHD according to DSM-5 Criteria. (American Psychiatric Association)

排除标准

  • •History of chronic/significant medical condition
  • •History or Current prescribed use of any psychotropics, including non-stimulant medications for ADHD.
  • •History or Current substance abuse or dependence.
  • •First degree relative with psychosis or bipolar disorder.
  • •Exclusion for the ADHD group only:
  • •Meets criteria for any other psychiatric comorbidity Disorder besides ADHD or Oppositional Defiant Disorder (ODD).
  • •Exclusion for the Healthy Control group only:
  • •Meets criteria for any psychiatric Disorders.

结局指标

主要结局

polysomnography to measure total sleep time(minutes) in ADHD patients

时间窗: 1 night

polysomnography to measure sleep efficiency(%) in ADHD patients

时间窗: 1 night

次要结局

  • Assessment of cognitive function in children and adolescents with Attention Deficit Hyperactivity Disorders(2 hours)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mustafa M. Hashem

Principal investigator

Assiut University

研究点 (1)

Loading locations...

相似试验