MedPath

Tetraspan 6 Percent (%) Combined With Sterofundin ISO Versus Albumin 5 Percent (%) Combined With Sodium Chloride (NaCL)

Phase 4
Terminated
Conditions
Renal Insufficiency
Interventions
Drug: Albumin + electrolyte solution
Registration Number
NCT00936247
Lead Sponsor
B. Braun Melsungen AG
Brief Summary

This investigational study will investigate two different volume replacement regimes in patients suffering from compromised renal function.

Detailed Description

Not available

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
2
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
1HES 130/0.42 + electrolyte solutionHES 130/0.42 + Sterofundin ISO
2Albumin + electrolyte solutionAlbumin + NaCl 0.9%
Primary Outcome Measures
NameTimeMethod
Impact of two different volume replacement regimes on base excess in patients with reduced renal functionfrom pre-operative assessment until last evaluation of data i.e. 5th (hospital) and 60th postoperative day (follow-up)
Secondary Outcome Measures
NameTimeMethod
Renal function, hemodynamics, blood loss, amount of given blood products, electrolytes, outcome and other data like concomitant medicationinta-/postoperative

Trial Locations

Locations (2)

Klinik für Anästhesiologie und operative Intensivmedizin, Klinikum der Stadt Ludwigshafen

🇩🇪

Ludwigshafen, Germany

Klinikum Mannheim gGmbH, Klinik für Anästhesiologie und Operative Intensivmedizin

🇩🇪

Mannheim, Germany

© Copyright 2025. All Rights Reserved by MedPath