Childhood Keratoconus - A Corneal Disease

Completed

• Conditions: Keratoconus,

• Registration Number: CTRI/2017/05/008578
• Lead Sponsor: All India Institute of Medical Sciences

Brief Summary

Aims & Objectives

To study the epidemiological & clinical features and management outcomes in cases of keratoconus in pediatric age group (<18 years).



Study Design: Prospective non-randomized interventional study

Inclusion Criteria :

Age: <18 years of age

Diagnosed cases of unilateral/bilateral KC.

Diagnosis of keratoconus will be based on the presence of the following three findings mandatorily16:

ï‚· Abnormal posterior corneal elevation

ï‚· Abnormal corneal thickness distribution

ï‚· Clinical non-inflammatory corneal thinning

Exclusion Criteria :

• Patients with any surgical intervention in the eye(s) done previously.

• Parents not willing to give consent for participation/follow-up.

Plan of Study:

Patients will be taken from the inpatient and outpatient department, Cornea Clinic and Contact Lens Clinic of Dr. Rajendra Prasad Centre for Ophthalmic Sciences and will be included or excluded based on the inclusion/exclusion criteria. Patients following up in period of 1 year of the study will be included. Institutional ethics committee approval has been obtained and tenets of Helsinki declaration shall be observed.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-01-12
• Last Update Posted: 2023-03-07

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Diagnosed cases of unilateral/bilateral KC in pediatric population (<18 years of age), recruited from Cornea Clinic and Contact Lens Clinic of R.P. Centre, AIIMS over a one year study period.

Exclusion Criteria

• Parents not willing to give consent for participation/follow-up.
• Patients with any ocular/systemic co-morbidity requiring immediate attention.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Demographic and clinical profile of keratoconus in pediatric age group	Once

Secondary Outcome Measures

Name	Time	Method
Management outcomes of keratoconus in pediatric age group	Day 0, Month 1, Month 3, Month 6 and Month 12.

Trial Locations

Locations (1)

All India institute of Medical Sciences; 🇮🇳 South, DELHI, India

All India institute of Medical Sciences

🇮🇳South, DELHI, India

Dr Yogita Gupta

Principal investigator

9868358359

yogitagupta30@gmail.com