ontuberculous mycobacterial cervicofacial lymphadenitis in children; diagnostic performance of the Capilia MAC antibody Elisa test and possible portals of entry
- Conditions
- Nontuberculous mycobacterial cervicofacial lymphadenitis/Atypical mycobacterial head and neck infcection of the lymph nodes10028440
- Registration Number
- NL-OMON56039
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 96
Study group:
• Age between 0-15 years
• High clinical suspicion of NTM cervicofacial lymphadenitis, as defined by
the following factors;
- Cervicofacial lymphadenopathy for a period longer than 3 weeks
- Typical clinical presentation as defined by Penn et al. (2011)
- Negative serologic tests for other kinds of (sub) chronical
lymphadenopathy: Epstein-Barr virus,
cytomegalovirus, Bartonella species, Adenovirus, and toxoplasmosis
- Ultrasonographically, hypoechoic lymph nodes, often with central necrosis,
nodal matting and adjacent soft tissue oedema
Control group:
• Age between 0-15 years
• Indication for surgery under general anesthesia
Study group:
- Known immunodeficiencies
- Usage of immunosuppressive drugs
Control group:
- Clinical suspicion of NTM cervicofacial lymphadenisis as defined above
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method