etrozole versus Mifepristone in abortion.
Phase 3
- Conditions
- Health Condition 1: O021- Missed abortion
- Registration Number
- CTRI/2024/07/070514
- Lead Sponsor
- AIIMS Patna
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
(1) women aged 18-45 years at 6–12 complete weeks of gestation seeking medication abortion
(2) having singleton pregnancy
(3) agreeing to participate in the trial voluntarily
(4) having no contraindications to medical abortion.
Exclusion Criteria
(1) incomplete, missed or inevitable miscarriage (defined by the clinical finding of an open cervix and bleeding)
(2) suspected ectopic pregnancy,
(3) history of heart, liver, kidney disease or adrenal insufficiency,
(4) abnormal uterine lesions such as adenomyosis, fibroids or congenital malformations or intrauterine adhesion
(5) pregnancy with an intrauterine contraceptive device in situ
(6) history of coagulatory dysfunction or intake of anticoagulant drugs and
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method proportion of complete expulsion rate with mifepristone and letrozole <br/ ><br>Timepoint: immediately after intervention, at 7 days and 15 days <br/ ><br>
- Secondary Outcome Measures
Name Time Method need for surgical evacuation <br/ ><br>Timepoint: at 15 days;time of expulsion of product of conception <br/ ><br>Timepoint: at 3 days and every 24 hours thereafter