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A Web-based Program to Help Caregivers of Lung Patients Learn About Available Supportive Care Resources

Not Applicable
Conditions
Stage II Lung Cancer
Stage IV Lung Cancer
Stage III Lung Cancer
Interventions
Other: Support for Caregiver - Generic List
Other: Support for Caregiver - Personalized List
Other: Internet-Based Intervention - CONNECT
Behavioral: Patient Navigation
Registration Number
NCT06383988
Lead Sponsor
Wake Forest University Health Sciences
Brief Summary

Clinical trial that tests the feasibility of a web based caregiver support resource, along with caregiver navigation sessions for caregivers of patients with stage II-IV lung cancer. The Caregiver Oncology Needs Evaluation Tool (CONNECT) is a novel web-based intervention designed for the community oncology setting, to systematically connect lung cancer caregivers with tailored supportive care resources. Lung cancer caregivers provide critical and challenging care for their loved ones and are at risk for their own negative psychosocial and physical outcomes. Implementing the CONNECT program along with caregiver navigation may provide additional support to caregivers of patients with stage II-IV lung cancer.

Detailed Description

This study is a multi-site randomized pilot trial enrolling 120 lung cancer caregiver-patient dyads (i.e., lung cancer caregivers (n=120) and their care-recipients (n=120)) across approximately 8-12 practices to assess the multi-site feasibility of a caregiver technology-based intervention (CONNECT) to identify caregivers' needs and connect them with supportive care resources. Caregivers will be randomized 1:1:1 to either the CONNECT intervention, usual care comparison group or generic resource list comparison group. CONNECT is a web-based intervention that empowers and educates caregivers about the benefits of supportive care services and systematically identifies unmet needs to connect lung cancer caregivers with tailored supportive care resources. The Central Caregiver Navigator will assist caregivers with resolving barriers to accessing resources and work with the Local Practice Referral Coordinator to process referrals. Caregivers and patients will complete measures at baseline (prior to caregiver randomization), and 12 and 24 weeks after baseline. Feasibility measures (retention, accrual rates, and participation) will be evaluated to inform the future trial. The Local Practice Referral Coordinator for each practice will report on time needed for practice participation, referral processes, and communication processes with the Central Caregiver Navigator.

Participants (i.e., patients or care-recipients) will be asked to complete study surveys at three time points:

* After consenting and before randomization of participant and caregiver. (Initial survey)

* Approximately 12 weeks after completing the first survey (12-week survey)

* Approximately 24 weeks after completing the first survey (24-week survey)

Each survey will take about 30-45 minutes to complete. The forms will ask about things such as demographics (gender, race, etc.), cancer symptoms, satisfaction with cancer care and health behaviors. You don't have to answer any question that makes you feel uncomfortable. These surveys can be done remotely over the internet, in the clinic, by phone or by mail.

Caregivers will also complete surveys at three time points and will be assigned to 1 of 3 study groups:

* Group 1 will be given the usual care provided at your clinic. At the completion of the study, this group will be given the generic supportive care resource list for their use that Group 2 received.

* Group 2 will be provided with a generic supportive care resource list.

* Group 3 will be asked to watch a brief video and complete the web-based CONNECT program either in the clinic or on your own device. The CONNECT program is designed to help identify any unmet needs and connect the caregiver with tailored supportive care resources, based on specific needs. The CONNECT Navigator will follow-up with within 2 business days of completion of the program and again 4 weeks later.

Caregiver Participants (Group 1, 2 and 3) will be asked to complete study surveys at three time points:

* After consenting and before randomization of participant and caregiver. (Initial survey)

* Approximately 12 weeks after completing the first survey (12-week survey)

* Approximately 24 weeks after completing the first survey (24-week survey)

Each survey will take about 35-45 minutes to complete. The forms will ask about things such as demographics (gender, race, etc.), caregiving experience, use of supportive care resources, quality of life, mood, and social needs (housing, transportation, utilities, etc). You don't have to answer any question that makes you feel uncomfortable.

Recruitment & Eligibility

Status
ENROLLING_BY_INVITATION
Sex
All
Target Recruitment
240
Inclusion Criteria
  • Must be ≥ 18 years of age, as this study is focused on the experience of adult patient-caregiver dyads
  • Must have a current diagnosis of new or recurrent stage II-IV lung cancer
  • Must be enrolled after the start of anticancer systemic therapy (+/- radiation therapy) with at least 9 weeks of any planned anticancer treatment remaining
  • Must be ambulatory and up (i.e., not bedridden) more than 50% of waking hours
  • Must s elf-report receiving unpaid care from a caregiver who meets the study caregiver criteria and who is willing to participate

Caregiver Inclusion Criteria:

  • Must be ≥18 years of age, as this study is focused on the experience of adult patient-caregiver dyads
  • Must self-report providing the majority of the unpaid care during cancer treatment for a patient who meets the patient criteria and who is willing to participate
  • Must have access to the internet at home or be willing to use CONNECT in the clinic
  • Must have access to telephone to complete sessions with the central caregiver navigator

Patient

Read More
Exclusion Criteria
  • Post-treatment survivors at the time of study enrollment
  • Enrolled in hospice care
  • Unable to read and English and not willing to have someone read surveys for them

Caregiver Exclusion Criteria:

  • Self-report currently receiving cancer treatment
  • Unable to read and communicate in English, as the CONNECT intervention is currently only available in English
Read More

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Group 1 (Standard care followed by generic resource list)Support for Caregiver - Generic ListCaregivers receive standard care and are then given a generic resource list at week 24.
Group 2 (Generic resource list)Support for Caregiver - Generic ListCaregiver receive a generic resource list at the start of the study.
Group 3 (CONNECT, personalized list, and navigation)Support for Caregiver - Personalized ListCaregivers receive access to the CONNECT tool, watch an educational video on self care and receive a personalized list of resources based on caregiver preferences. Caregivers also receive access to and complete at least 2 calls, at baseline and at week 4, with a caregiver navigator to review the resource list and address any additional needs.
Group 3 (CONNECT, personalized list, and navigation)Patient NavigationCaregivers receive access to the CONNECT tool, watch an educational video on self care and receive a personalized list of resources based on caregiver preferences. Caregivers also receive access to and complete at least 2 calls, at baseline and at week 4, with a caregiver navigator to review the resource list and address any additional needs.
Group 3 (CONNECT, personalized list, and navigation)Internet-Based Intervention - CONNECTCaregivers receive access to the CONNECT tool, watch an educational video on self care and receive a personalized list of resources based on caregiver preferences. Caregivers also receive access to and complete at least 2 calls, at baseline and at week 4, with a caregiver navigator to review the resource list and address any additional needs.
Primary Outcome Measures
NameTimeMethod
Caregiver retention at 12 weeksAt 12 weeks

Calculated as the following: Number of caregivers who complete at least 75% of the 12-week assessments divided by the number randomized. Retention will be estimated and reported along with an exact 95% confidence interval.

Secondary Outcome Measures
NameTimeMethod
Caregiver participationUpon completion of recruitment, approximately 12 months

Proportion of eligible caregivers who agreed to participate

Caregiver accrual rateUpon completion of recruitment, approximately 12 months

Number of caregivers who agree to participate divided by the number of months of recruitment

Desired modality for training (e.g., live webinar, recorded video, paper materials) for Local Practice Referral CoordinatorAt completion of training, up to 6 months

Will be summarized using appropriate descriptive statistics.

Frequency of needed resource updates in the CONNECT databaseUp to completion of practice intervention activities, an average of 18 months

Will be summarized across practices using mean, median, standard deviation and interquartile range

Average time (minutes) spent by the Central Caregiver Navigator and Local Practice Referral Coordinators with each caregiver in the CONNECT armUp to completion of practice intervention activities, an average of 18 months

Will be summarized across practices using mean, median, standard deviation and interquartile range.

Modalities used for communication (e.g., phone, virtual web meeting, email) for Central Caregiver Navigator and Local Practice Referral CoordinatorUp to completion of practice intervention activities, an average of 18 months

Will be summarized using appropriate descriptive statistics.

Caregiver retention at 24 weeksAt 24 weeks

Number of caregivers who complete at least 75% of the 24-week assessments divided by the number randomized.

Caregiver acceptabilityAt 12 weeks

Self-report survey developed for this study to assess the degree to which caregivers found different aspects of CONNECT, the generic resource list, or usual care helpful using a Likert response from 0 (Not at all) to 5 (Very Much)

Modality of contact (e.g. phone, virtual web meeting, email) made by the Central Caregiver Navigator and Local Practice Referral Coordinators with each caregiver in the CONNECT armUp to completion of practice intervention activities, an average of 18 months

Will be summarized using appropriate descriptive statistics.

Number of referrals facilitated by the Local Practice Referral Coordinator and Central Caregiver NavigatorUp to completion of practice intervention activities, an average of 18 months

Will be summarized across practices using mean, median, standard deviation and interquartile range.

Improvements for the future trial from Local Practice Referral Coordinator's perspectives from a survey at the end of the studyAt completion of practice intervention activities, an average of 18 months

Will be summarized using appropriate descriptive statistics.

Average time (minutes) needed for training for Local Practice Referral CoordinatorAt completion of training, up to 6 months

Will be summarized across practices using mean, median, standard deviation and interquartile range.

Average time (minutes) needed to identify and enter local resources into the Caregiver Oncology Needs Evaluation Tool (CONNECT) databaseAt conclusion of practice intervention activities, an average of 18 months

Will be summarized across practices using mean, median, standard deviation and interquartile range.

Type of referrals (e.g., in person, online) facilitated by the Local Practice Referral Coordinator and Central Caregiver NavigatorUp to completion of practice intervention activities, an average of 18 months

Will be summarized using appropriate descriptive statistics.

Number of contacts made by the Central Caregiver Navigator and Local Practice Referral Coordinators with each caregiver in the CONNECT armUp to completion of practice intervention activities, an average of 18 months

Will be summarized across practices using mean, median, standard deviation and interquartile range.

Average time (minutes) needed to communicate for Central Caregiver Navigator and Local Practice Referral CoordinatorUp to completion of practice intervention activities, an average of 18 months

Will be summarized across practices using mean, median, standard deviation and interquartile range.

Trial Locations

Locations (24)

Montefiore Medical Center-Einstein Campus

🇺🇸

Bronx, New York, United States

Community Medical Center

🇺🇸

Scranton, Pennsylvania, United States

Geisinger Wyoming Valley/Henry Cancer Center

🇺🇸

Wilkes-Barre, Pennsylvania, United States

Baptist Memorial Hospital and Cancer Center-Collierville

🇺🇸

Collierville, Tennessee, United States

Kaiser Permanente-Franklin

🇺🇸

Denver, Colorado, United States

Kaiser Permanente - Rock Creek

🇺🇸

Lafayette, Colorado, United States

Kaiser Permanente - Lone Tree

🇺🇸

Lone Tree, Colorado, United States

Augusta University Medical Center

🇺🇸

Augusta, Georgia, United States

Baptist Memorial Hospital and Cancer Center-Golden Triangle

🇺🇸

Columbus, Mississippi, United States

Baptist Cancer Center-Grenada

🇺🇸

Grenada, Mississippi, United States

Baptist Memorial Hospital and Cancer Center-Union County

🇺🇸

New Albany, Mississippi, United States

Baptist Memorial Hospital and Cancer Center-Oxford

🇺🇸

Oxford, Mississippi, United States

Baptist Memorial Hospital and Cancer Center-Desoto

🇺🇸

Southhaven, Mississippi, United States

Lake Regional Hospital

🇺🇸

Osage Beach, Missouri, United States

CoxHealth South Hospital

🇺🇸

Springfield, Missouri, United States

Wake Forest NCORP Research Base

🇺🇸

Winston-Salem, North Carolina, United States

Gibbs Cancer Center-Gaffney

🇺🇸

Gaffney, South Carolina, United States

Prisma Health Cancer Institute - Butternut

🇺🇸

Greenville, South Carolina, United States

Prisma Health Cancer Institute - Eastside

🇺🇸

Greenville, South Carolina, United States

Gibbs Cancer Center-Pelham

🇺🇸

Greer, South Carolina, United States

Spartanburg Medical Center

🇺🇸

Spartanburg, South Carolina, United States

MGC Hematology Oncology-Union

🇺🇸

Union, South Carolina, United States

Baptist Memorial Hospital and Cancer Center-Memphis

🇺🇸

Memphis, Tennessee, United States

ThedaCare Regional Cancer Center

🇺🇸

Appleton, Wisconsin, United States

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