临床试验/NCT01775384

NCT01775384已完成不适用

Influence of a Polyphenol-enriched Protein Powder on Exercise-induced Inflammation and Oxidative Stress in Athletes: a Metabolomics Approach

Appalachian State University2 个研究点分布在 1 个国家目标入组 34 人开始时间: 2012年4月最近更新: 2013年1月25日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方: Appalachian State University
入组人数: 34
试验地点: 2
主要终点: Metabolomics; change in metabolites over time

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

Nutrasorb is a newly developed food product (see www.nutrasorb.com). This study will use the Nutrasorb soy protein product that is matrixed with polyphenols from blueberries and green tea extract, and test for efficacy as a nutritional countermeasure to exercise-induced physiologic stress (i.e., immune dysfunction, inflammation, and oxidative stress) using both traditional and metabolomics-based outcome measures.

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Parallel
主要目的: Treatment
盲法: Double (Participant, Investigator)

入排标准

年龄范围: 18 Years 至 55 Years（Adult）
性别: All
接受健康志愿者: 是

入选标准

•Male or female endurance athletes; competitive runners or cyclists
•Capable of exercising for 2.5 h at a high intensity in the lab
•Ages 18-55
•Agree to train normally and stay weight stable.
•Agree to avoid the use of large dose vitamin/mineral supplements
•Agree to avoid herbs and medications that influence inflammation

排除标准

•Regularly take supplements or medicines known to effect inflammation.
•At moderate or high risk for cardiovascular disease.
•Younger than 18 or older than 55 years of age.
•No history of competing in long distance running and cycling races.

结局指标

主要结局

Metabolomics; change in metabolites over time

时间窗: 18-day period; Blood samples collected pre- and post-14 d supplementation, and immediately and 14 h after the third day of running

GC-MS and LC-MS through Metabolon

次要结局

Change in inflammation(18-day period; Blood samples collected pre- and post-14 d supplementation, and immediately and 14 h after the third day of running)
Change in oxidative stress(18-day period; Blood samples collected pre- and post-14 d supplementation, and immediately and 14 h after the third day of running)
Change in immune function(18-day period; Blood samples collected pre- and post-14 d supplementation, and immediately and 14 h after the third day of running)

研究者

发起方

Appalachian State University

申办方类型

Other

责任方

Sponsor

研究点 (2)

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