Can a seaweed supplement reduce your risk of diabetes?

Not Applicable

Completed

• Conditions: Postprandial glycaemic response; Diabetes; Metabolic and Endocrine - Diabetes; Alternative and Complementary Medicine - Other alternative and complementary medicine

• Registration Number: ACTRN12616000126415
• Lead Sponsor: Monash University, Department of Nutrition and Dietetics

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-02-04
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Body mass index from 18.5 to less than 28 kg/m2, a fasting blood glucose level below 5.5 mmol/L and blood pressure within the normal range.

Exclusion Criteria

1. Gastrointestinal issues that may affect the absorption and intestinal actions of the polyphenols,
2. Taking medication for blood sugar control,
3. Taking other natural health products known to impact on polyphenols e.g. fish oil,
4. Breastfeeding or pregnant,
5. Have any of the following serious health conditions:
i. liver/thyroid issues,
ii. hypertension,
iii. recent major surgery,
6. Consume more than 4 standard drinks per day, or 9 standard drinks per week,
7. Smoker,
8. Have an implanted cardiac defibrillator.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Postprandial blood glucose incremental area under the curve[Blood samples taken at -45, -30, 15, 30, 45, 60, 90 and 120 minutes after test drink.];Postprandial blood insulin incremental area under the curve[Blood samples taken at -30, 30, 60, 90 and 120 minutes after test drink.]

Secondary Outcome Measures

Name	Time	Method
Postprandial blood glucose 'time to peak'[Blood samples taken at -45, -30, 15, 30, 45, 60, 90 and 120 minutes after test drink.];Postprandial blood insulin 'time to peak'[Blood samples taken at -30, 30, 60, 90 and 120 minutes after test drink.];How timing of supplementation, whether administered in the morning (~7 am) or evening (~6 pm), affects polyphenol impact on postprandial blood glucose and insulin incremental area under the curve and 'time to peak'.[Blood samples taken at -45, -30, 15, 30, 45, 60, 90 and 120 minutes after test drink for glucose.<br>Blood samples taken at -30, 30, 60, 90 and 120 minutes after test drink for insulin.];Intolerance symptoms - assessed by participant completion of a questionnaire designed specifically for this study.[24 hours from supplement ingestion]