Day of Embryo Transfer for Patients Undergoing In Vitro Fertilization

Not Applicable

Completed

• Conditions: Infertility
• Interventions: Procedure: Day 2 embryo transfer; Procedure: Day 3 embryo transfer

• Registration Number: NCT00615771
• Lead Sponsor: Stanford University

Brief Summary

We are examining whether pregnancy rates differ based on day of embryo transfer in patients who replace all available embryos after an In vitro Fertilization (IVF) cycle. Patients must be undergoing IVF treatment at Stanford University and patients will not receive compensation for their participation (no medical costs covered or patient payment for participation).

Detailed Description

The decision on the number of embryos to transfer after an IVF cycle is based on the number of available embryos, the quality of the embryos, the patient's age, and the goal of limiting multiple gestations. Stanford Fertility Center and most IVF centers examine the embryos on the third day after oocyte (egg) retrieval to select for the best quality embryos to transfer, and depending on quality, the remaining embryos are frozen to be used in the future. Patients with a limited number of embryos, those that plan to replace all available embryos after an IVF cycle, do not need to wait until the third day after oocyte retrieval to select embryos, and may replace the embryos on the second day after the oocyte retrieval. We are examining whether pregnancy rates differ among these patients based on the day of embryo transfer (Day 2 vs. Day3). Patients must be undergoing IVF treatment at Stanford University and patients will not receive compensation for their participation (no medical costs covered or patient payment for participation).

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2007-01
• Study First Submitted: 2008-02-01
• Study First Submitted QC: 2008-02-01
• Study First Posted: 2008-02-14
• Primary Completion: 2009-03
• Study Completion: 2009-03
• Status Verified: 2011-07
• Last Update Submitted: 2016-11-23
• Last Update Posted: 2016-11-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 242

Inclusion Criteria

Patients undergoing fresh IVF cycle at Stanford Fertility Center who plan on replacing all available embryos.

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Exclusion Criteria

Patients that do not meet above criteria.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Day 2 embryo transfer	Day 2 embryo transfer	Embryos are transferred 2 days after fertilization.
Day 3 embryo transfer	Day 3 embryo transfer	Standard of care for women undergoing IVF with a limited number of embryos is to transfer all embryos on Day 3 after fertilization

Primary Outcome Measures

Name	Time	Method
Pregnancy rates	1 year

Secondary Outcome Measures

Name	Time	Method
Live birth rates	1 year
Multiple gestation rates	1 year

Trial Locations

Locations (1)

Stanford University School of Medicine; 🇺🇸 Stanford, California, United States