PET scan for measuring response in lymphoma of brai
Not Applicable
- Conditions
- Health Condition 1: C859- Non-Hodgkin lymphoma, unspecified
- Registration Number
- CTRI/2021/05/033776
- Lead Sponsor
- Tata Memorial Centre Mumbai
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Diagnosed cases of PCNSL
2.Receiving high dose methotrexate based induction therapy
3.Patient available for response assessment MRI & PET-CT Brain post induction chemotherapy
4.Patient able to understand & sign the consent.
Exclusion Criteria
1.Patients who cannot complete the high dose methotrexate based induction chemotherapy due to toxicity or other reasons except progression .
2.Patient with any contrast allergies or hypersensitivities.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sensitivity and specificity of PET-CT as compared to MRI (gold standard for response assessment)Timepoint: 2,4 and 6 months
- Secondary Outcome Measures
Name Time Method Prognostic value of MTV and TLGTimepoint: At start that time point 0;Prognostic value of PET responseTimepoint: 2, 4 and 6 months;Utility of PET-MRI fusionTimepoint: 2,4 and 6 months