Efficiency of Controlled Drug Release Dressings Using Biopolymers with Antibiotics and Anti-inflammatory Nanoparticles for Patients with Open Wound

Phase 2

Recruiting

• Conditions: Adults with acute open wound; Efficiency, Dressing, Biopolymers, Nanoparticles, Open Wound

• Registration Number: TCTR20240422009
• Lead Sponsor: Walailak university

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-04-22
• Last Update Posted: 19 August 2024
• Study Completion: 2025-04-13

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1). Age 18-50 year 2). Will to participate the study 3).Acute open wound

Exclusion Criteria

1).History of allergy including lactic acid, polyvinyl alcohol, carboxymethyl cellulose, polyethylene glycol diacrylate, acetic acid, hyaluronic acid, povidone-iodine or vancomycin 2).Currently treated with other wound care 3).Pregnancy or lactation 4).Immunocompromised status or currently on immunosuppressive agents

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Infection scores Week 0 and week 4 UPPERLOWER score (Unhealthy tissue, Pain, Poor healing, Exudate, Reek, Larger in size, Osseous tissue, Warmth, Edema, Redness)

Secondary Outcome Measures

Name	Time	Method
Adverse reactions Week 1, 2, 3, and 4 Adverse reactions,Quality of life Week 0 and 4 Quality of life scores,Itch Week 1, 2, 3, and 4 Itch scores,Pain Week 1, 2, 3, and 4 Pain score,Satisfaction Week 4 Satisfaction level