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Clinical Trials/NL-OMON56339
NL-OMON56339
Not Yet Recruiting
N/A

Assessment of myocardial function, endothelial function and perFUSION in early and advanced disease stages of Hypertrophic CardioMyopathy: FUSION-HCM - FUSION-HCM

Amsterdam UMC0 sites100 target enrollmentTBD
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Overview

Phase
N/A
Intervention
Not specified
Conditions
Not specified
Sponsor
Amsterdam UMC
Enrollment
100
Status
Not Yet Recruiting
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
2 years ago
Study Type
Observational invasive

Investigators

Sponsor
Amsterdam UMC

Eligibility Criteria

Inclusion Criteria

  • •MYBPC3 mutation carrier
  • •MYH7 mutation carrier
  • •Genotype\-negative first degree relative of a MYBPC3 or MYH7 mutation carrier

Exclusion Criteria

  • •\>\=70 years old
  • •Insulin\-dependent diabetes mellitus
  • •Claustrophobia
  • •Pacemaker/ICD
  • •Renal insufficiency \<30 GFR
  • •Hypertension (systolic \>140mmHg or diastolic \>90mmHg)
  • •For the genotype negative group, no phenotype group, and mild phenotype group:
  • •the use of blood pressure medication (diuretics, beta\-blockers, ACE\-inhibitors,
  • •angiotensin II receptor blockers, calcium channel blockers, alpha blockers)
  • •For the HCM phenotype group: when it is unsafe to withhold from blood pressure

Outcomes

Primary Outcomes

Not specified

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