Using Personalized Assessments in the Treatment of Childhood OCD

Not Applicable

Recruiting

• Conditions: Obsessive-Compulsive Disorder

• Registration Number: NCT06407648
• Lead Sponsor: Johns Hopkins University

Brief Summary

The primary purpose of this study is to learn whether personalized assessment of obsessive-compulsive disorder (OCD) symptoms in childhood OCD using mobile health technology are feasible and acceptable for youth and parents. The investigators will also examine whether personalized cognitive-behavioral therapy (CBT) that is informed by personalized OCD assessments yields better clinical outcomes when compared to standard CBT for youth with OCD

Detailed Description

Not available

Study Timeline

• Study Start: 2024-04-03
• Study First Submitted: 2024-05-06
• Study First Submitted QC: 2024-05-06
• Study First Posted: 2024-05-09
• Status Verified: 2025-05
• Last Update Submitted: 2025-05-14
• Last Update Posted: 2025-05-18
• Primary Completion: 2026-06-30
• Study Completion: 2026-12-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1. be 8-17 years of age;
2. meet diagnostic criteria for a primary diagnosis of OCD on a structured clinical interview;
3. have moderate OCD severity as evidenced by a CY-BOCS total score of ≥16;
4. medication free and/or on a stable dose of medication 8 weeks prior to study participation;
5. be English speaking.

Exclusion Criteria

1. the presence of psychotic disorder, bipolar disorder, or autism spectrum disorders;
2. significant suicidal ideation that warrants medical intervention;
3. concurrent psychotherapy for OCD;
4. inability to complete scales, or attend visits.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Children's Yale-Brown Obsessive-Compulsive Scale Second Edition (CY-BOCS-II) Total Severity Score	Screen, Baseline (Week 0), Week 4, Week 8, and Week 12	A clinician-rated measure of OCD symptom severity in the past week. This 10-item measure is rated on a 0 to 5 scale with a total score ranging from 0 to 50. A higher total score is reflective of greater OCD symptom severity.

Trial Locations

Locations (1)

Johns Hopkins University School of Medicine; 🇺🇸 Baltimore, Maryland, United States