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临床试验/NCT07243613
NCT07243613已完成不适用

Acute Psychoneuroendocrine Responses to Maximal Exertion Following High-Load Training in Elite Rowers: A Sex-Based Comparative Study

Poznan University of Physical Education1 个研究点 分布在 1 个国家目标入组 28 人开始时间: 2024年3月15日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
28
试验地点
1
主要终点
Serum Testosterone concentration

研究概览

简要总结

This study examined how the body and mood respond to intense physical effort in elite male and female rowers. Athletes completed a maximal rowing test after one week of hard training. Researchers collected blood samples before and after exercise to measure stress hormones and brain-related chemicals. They also used a short questionnaire to assess how the athletes felt emotionally before the test. The goal of the study is to better understand how physical and mental fatigue develop in well-trained athletes, and whether men and women respond differently.

详细描述

This observational cohort study was designed to characterize acute physiological and psychological responses to maximal exertion following a high-load training period in elite male and female rowers. The main aim was to investigate how accumulated training fatigue affects hormonal and neurochemical responses to intense effort, and whether these responses differ by sex.

Participants were national-level athletes undergoing a standardized 7-day training camp, during which they completed identical high-intensity training sessions. On day 8, all participants performed a 2000-m maximal rowing ergometer test under controlled conditions. Blood samples were collected at three time points: before exercise (PRE), immediately post-exercise (POST), and 1 hour post-exercise (1H).

Biomarkers analyzed in serum included cortisol, total testosterone, serotonin (5-HT), dopamine (DA), gamma-aminobutyric acid (GABA), and tryptophan. The testosterone-to-cortisol (T/C) ratio was used as an index of anabolic-catabolic balance, while the 5-HT/DA ratio was examined as a neurochemical indicator of central fatigue.

In parallel, mood state was assessed once prior to the exertion test using the standardized Profile of Mood States (POMS) questionnaire. This provided insight into psychological readiness and emotional state entering maximal effort.

A total of 28 athletes (12 females, 16 males) completed the full protocol. There were no missing data. The study did not involve any interventions, randomization, or masking. Statistical analyses included repeated-measures ANOVA for time and group effects, and calculation of within-group effect sizes (Cohen's d).

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
19 Years 至 25 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Aged 19-25 years National-level competitive rower Minimum 5 years of structured rowing training Currently in full training and competition season Completed 7-day standardized high-load training program Provided written informed consent

排除标准

  • Use of medications or supplements affecting hormonal or neurochemical markers Known endocrine, neurological, or psychiatric disorders Injury or illness interfering with training or testing Incomplete participation in the training camp or testing protocol

结局指标

主要结局

Serum Testosterone concentration

时间窗: Before exercise, immediately after, and 1 hour after recovery

Testosterone concentration will be measured in serum using immunoassay. Units: ng/mL.

Serum Cortisol concentration

时间窗: Before exercise, immediately after, and 1 hour after recovery

Cortisol concentration will be measured in serum using an immunoassay. Units: ng/mL

Serum Serotonin concentration

时间窗: Before exercise, immediately after, and 1 hour after recovery

Serotonin concentration will be measured in serum using an immunoassay. Units: ng/mL

Serum Gamma-aminobutyric acid (GABA) concentration

时间窗: Before exercise, immediately after, and 1 hour after recovery

GABA concentration will be measured in serum using an immunoassay. Units: µg/dL

Serum Tryptophan concentration

时间窗: Before exercise, immediately after, and 1 hour after recovery

Tryptophan concentration will be measured in serum using an immunoassay. Units: µg/dL

Profile of Mood States

时间窗: Before exercise

Self-reported mood assessed using the Profile of Mood States (POMS); total and subscale scores.

次要结局

  • T:C ratio(Before exercise, immediately after, and 1 hour after recovery)
  • S:D ratio(Before exercise, immediately after, and 1 hour after recovery)

研究者

发起方
Poznan University of Physical Education
申办方类型
Other
责任方
Sponsor

研究点 (1)

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