Low and Moderete Flow Anaesthesia on Haemodynamics

Not Applicable

Not yet recruiting

• Conditions: Hemodynamics Instability; Arrhythmias Cardiac; Cerebral Oxygenation

• Registration Number: NCT06871371
• Lead Sponsor: Umraniye Education and Research Hospital

Brief Summary

The study topic investigates the potential advantages of low-flow anesthesia in terms of physiological protection and resource saving.

Detailed Description

The study aims to compare the effects of low and normal flow sevoflurane anesthesia on the frontal QRS-T angle and cerebral oxygenation in laparoscopic cholecystectomy surgery. The primary objective was to evaluate the effects of low-flow anesthesia on hemodynamic stability and arrhythmia risk; the secondary objective was to compare the total sevoflurane consumption in both methods.

Study Timeline

• Study First Submitted: 2025-01-26
• Status Verified: 2025-03
• Study First Submitted QC: 2025-03-06
• Last Update Submitted: 2025-03-06
• Study First Posted: 2025-03-11
• Last Update Posted: 2025-03-11
• Study Start: 2025-03-15
• Primary Completion: 2025-04-15
• Study Completion: 2025-04-15

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 76

Inclusion Criteria

• being ASA1-2 status
• between the ages of 18-70
• who are planned for laparoscopic cholecystectomy

Exclusion Criteria

• Patients who refuse to give informed consent
• Pregnant and breastfeeding patients
• Morbidly obese patients (Body mass index over 40)
• Patients with uncontrolled diabetes mellitus, with serious cardiovascular, pulmonary, renal, hepatic disease, obstructive sleep apnea, with electrolyte imbalance- Those with a history of alcohol or drug abuse, with perioperative hemodynamic instability
• Patients using drugs known to prolong myocardial repolarization
• inability to increase SPO2 above 95 despite necessary intervention

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
the effects of low-flow anesthesia on hemodynamic stability	in 2 months	The primary objective was to detect the adverse effects of low-flow anesthesia on hemodynamic stability and arrhythmia risk

Secondary Outcome Measures

Name	Time	Method
the cerebral oxygenation	in 2 months	The primary objective was to detect the adverse effects of low-flow anesthesia on cerebral oxygenation

Trial Locations

Locations (1)

Umraniye Education and research hospital; 🇹🇷 Istanbul, Turkey