Follow-up after treatment of Neisseria gonorrhoeae infections, when and how is a test-of-cure to be included in routine? A prospective observational cohort study

Completed

• Conditions: gonorrhoea; Neisseria gonorrhoeae; 10004018; 10016417; 10040785

• Registration Number: NL-OMON38963
• Lead Sponsor: GGD Amsterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

18 years or older
Infection with Neisseria gonorrhoeae of urethra, vagina/cervix and/or anal canal
Infection with Neisseria gonorrhoeae diagnosed by Gram-stained smear, APTIMA Combo 2 (NAAT) and/or direct cultivation
Willing to receive the routine treatment for Ng

Exclusion Criteria

Use of antibiotics one week prior to gonorrhoea treatment
Current pregnancy in females
Only urethral infection in females
Ng infections diagnosed by Gram-stained smear, but subsequently not confirmed by NAAT or cultivation.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary endpoints are clearance of Ng infection and time to clearance in<br /><br>days determined by NAAT. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary endpoints are clearance per anatomical location and intermittent<br /><br>presence of bacterial DNA and/or RNA.</p><br>