Serial CT Angiography of atherosclerotic carotid plaque:determinants and prognosis of change in volume, composition and morphology

Recruiting

• Conditions: atherosclerosis; 10003216

• Registration Number: NL-OMON33613
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 300

Inclusion Criteria

- Patients with cerebrovascular symptoms (amaurosis fugax, hemispheric TIA or minor stroke (Rankin < 3)) who had visited the department of Neurology. The neurologist examined the patient and decided whether the neurological symptoms can be considered to be caused by cerebral ischemia
- Patients had undergone MDCTA of the carotid arteries
- the presence of atherosclerotic disease in the carotid artery as seen on
MDCTA.
- signed Informed consent

Exclusion Criteria

·contrast material allergy
·renal insufficiency defined as eGFR <= 60 mL/min
·no informed consent

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Change in atherosclerotic plaque volume, plaque composition and plaque<br /><br>morphology in the carotid artery</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>1) Recurrent ipsilateral cerebrovascular event.<br /><br>2) Ischemic stroke, myocardial infarction or vascular death</p><br>