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The efficacy of isotretinoin plus NB-UVB in the treatment of psoriasis vulgaris

Phase 2
Conditions
Psoriasis vulgaris.
psoriasis vulgaris
Registration Number
IRCT138812213543N1
Lead Sponsor
Behestan Darou (P.J.S)
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
30
Inclusion Criteria

Patients with chronic plaque type psoriasis (psoriasis vulgaris) who are candidates for phototherapy
Exclusion criteria: female patients who do not have a safe contraception or want to become pregnant in less than 1 month, patient with abnormal lipid profile tests, liver function tests and ANA

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Improvement of severity of psoriasis vulgaris. Timepoint: First visit, 4 weeks, 10 weeks, 14 weeks after starting therapy. Method of measurement: PASI score.
Secondary Outcome Measures
NameTimeMethod
Complications (nausea, pruritus, erythrodermia). Timepoint: First visit, 4 weeks, 10 weeks, and 14 weeks after starting therapy. Method of measurement: clinical examination.
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