Inspiratory Effort in COVID-19

Recruiting

• Conditions: Acute Respiratory Failure; Covid19

• Registration Number: NCT04666246
• Lead Sponsor: University of Modena and Reggio Emilia

Brief Summary

This study aims at assessing esophageal pressure in patients with acute respiratory failure due to COVID-19 undergoing non invasive respiratory support.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-03-01
• Study First Submitted: 2020-12-11
• Study First Submitted QC: 2020-12-11
• Study First Posted: 2020-12-14
• Primary Completion: 2024-06-01
• Status Verified: 2025-04
• Last Update Submitted: 2025-04-24
• Last Update Posted: 2025-04-25
• Study Completion: 2030-02-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• COVID-19
• Acute respiratory failure undergoing non-invasive respiratory support

Exclusion Criteria

• Need for immediate endotracheal intubation
• Chronic respiratory diseases

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Inspiratory effort quantification	24 hours from admission	Esophageal pressure assessment through dedicated esophageal pressure transducer

Secondary Outcome Measures

Name	Time	Method
Non invasive respiratory support failure	24 hours	Reaching of the criteria for endotracheal intubation

Trial Locations

Locations (1)

University Hospital of Modena; 🇮🇹 Modena, Italy