NCT01572961
Completed
Not Applicable
Amélioration Des Techniques d'étude de la Micro-cirulation cutanée Chez Des Sujets Sains
University Hospital, Angers1 site in 1 country16 target enrollmentNovember 2010
ConditionsPhysiology of Microvascular Skin
Overview
- Phase
- Not Applicable
- Intervention
- acetylsalicilic acids (Aspirin)
- Conditions
- Physiology of Microvascular Skin
- Sponsor
- University Hospital, Angers
- Enrollment
- 16
- Locations
- 1
- Primary Endpoint
- The increase of Laser Doppler Blood Flow after the second current stimulation
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
Current stimulation induces microvascular dilation in human skin. The investigators aimed to study (1) whether the current vasodilation is amplified after two segmental current stimulation as compared to one stimulation; (2) whether this amplification relies on prostaglandin-sensitive mechanisms. A double-blind randomized placebo-controlled crossover trial is conducted in Angers, France.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age \> or equal to 18 years old
- •Healthy subjects
Exclusion Criteria
- •Aspirin allergy
Arms & Interventions
Aspirin
Aspirin
Intervention: acetylsalicilic acids (Aspirin)
Placebo
Placebo
Intervention: Placebo
Outcomes
Primary Outcomes
The increase of Laser Doppler Blood Flow after the second current stimulation
Time Frame: 1 hour
Secondary Outcomes
- The increase of Laser Doppler Blood Flow after the second current stimulation after aspirin administration(1 hour)
Study Sites (1)
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