Microvascular Function Assessment in Healthy Subjects
- Conditions
- Physiology of Microvascular Skin
- Interventions
- Drug: PlaceboDrug: acetylsalicilic acids (Aspirin)
- Registration Number
- NCT01572961
- Lead Sponsor
- University Hospital, Angers
- Brief Summary
Current stimulation induces microvascular dilation in human skin. The investigators aimed to study (1) whether the current vasodilation is amplified after two segmental current stimulation as compared to one stimulation; (2) whether this amplification relies on prostaglandin-sensitive mechanisms. A double-blind randomized placebo-controlled crossover trial is conducted in Angers, France.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 16
- Age > or equal to 18 years old
- Healthy subjects
- Aspirin allergy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Placebo Placebo Placebo Aspirin acetylsalicilic acids (Aspirin) Aspirin
- Primary Outcome Measures
Name Time Method The increase of Laser Doppler Blood Flow after the second current stimulation 1 hour
- Secondary Outcome Measures
Name Time Method The increase of Laser Doppler Blood Flow after the second current stimulation after aspirin administration 1 hour
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
Trial Locations
- Locations (1)
University Hospital
🇫🇷Angers, Maine et Loire, France
University Hospital🇫🇷Angers, Maine et Loire, France