Detecting low allele frequency of compound minor mutation using high-sensitivity next generation sequencer for EGFR mutant lung cancer
Not Applicable
Recruiting
- Conditions
- EGFR-mutant lung cancer
- Registration Number
- JPRN-UMIN000037133
- Lead Sponsor
- St. Marianna University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
Other cases attending physician it is determined unsuitable for registration of the study
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Detection rate of EGFR compound minor mutation using NGS
- Secondary Outcome Measures
Name Time Method 1) Allele frequency of sensitive mutation and compound minor mutation, and its corelation for response rate and PFS. 2) T790M detection rate at diagnostic phase and re-biopsy phase 3) Subsequent allele frequency change of EGFR compound minor mutation