Functional Imaging during Radiation Therapy for HNC using FDG-PET, HX4-PET and MRI - FAITH

Antoni van Leeuwenhoek Ziekenhuis0 个研究点目标入组 56 人开始时间: 待定最近更新: 2024年4月23日

适应症

试验速览

暂无简介。

•- Histologic biopsy confirmed SCC oral cavity, oropharynx, hypopharynx, and larynx
•- HPV negative tumors
•- Largest tumor diameter at least 3 cm (primary tumor)
•- Scheduled for concurrent chemoradiotherapy or definitive external beam radiotherapy (DAHANCA schedule and normal fractionation are both applicable)

•- SCC of the nasopharynx, nasal cavity, paranasal sinuses, salivary gland and thyroid gland
•- Expected failure from follow-up
•- Patients who are not expected to participate in at least 2 out of 3 imaging modalities (MRI, HX4-PET and FDG-PET)
•- Pregnancy or lactation
•- Patients (M/F) with reproductive potential not implementing adequate contraceptives measures at least 14 days before the first study procedure
•- Prior surgery, radiotherapy or chemotherapy for this tumor
•- Previous malignancies within the last 2 years except for adequately treated basal cell carcinoma of the skin and carcinoma in situ of the cervix

发起方

Antoni van Leeuwenhoek Ziekenhuis