Studying the effectiveness of different Steroids in treatment of COVID-19
Not Applicable
- Conditions
- Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere
- Registration Number
- CTRI/2021/10/037112
- Lead Sponsor
- Dr Sujith Vasireddy
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1)PCR confirmed COVID-19 infection
2)PaO2/FiO2 < 200 mmHg
3)Positive pressure ventilation (non-invasive or invasive) or high flow nasal cannula (HFNC) higher than 45 L/min for less than 48 hours
4)Requiring ICU admission
Exclusion Criteria
1)pregnancy;
2)Severe underlying disease, i.e. end stage of malignancy disease or end stage of pulmonary disease;
3)Underlying disease requiring corticosteroids;
Contraindication for corticosteroids
4)Diseases causing an immunocompromised state, i.e AIDS.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ALL CAUSE MORTALITYTimepoint: Till discharge from the hospital
- Secondary Outcome Measures
Name Time Method Cardiac complicationsTimepoint: After administration of steroid till discharge from the hospital;Development of ARDSTimepoint: After administration of steroid till discharge from the hospital;Length of hospital StayTimepoint: till discharge from the hospital;New requirement of ventilatory supportTimepoint: After administration of steroid till discharge from the hospital;Number of days of oxygen supportTimepoint: till discharge from the hospital;PneumoniaTimepoint: After administration of steroid till discharge from the hospital;Renal complicationsTimepoint: After administration of steroid till discharge from the hospital;SepsisTimepoint: After administration of steroid till discharge from the hospital;Steroid induced complicationTimepoint: After administration of steroid till discharge from the hospital;Transfer to ICUTimepoint: After administration of steroid till discharge from the hospital;Vascular ComplicationsTimepoint: After administration of steroid till discharge from the hospital