Incidence, Risk Factors and Impact of Significant Pain in Patients Undergoing Neurosurgery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Postoperative Pain
- Sponsor
- National Institute of Mental Health and Neuro Sciences, India
- Enrollment
- 1000
- Locations
- 1
- Primary Endpoint
- Postoperative pain using Numerical Rating Scale
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
The proposed study intends to evaluate incidence of postoperative pain after neurosurgery. This study is likely to help in understanding of the magnitude of this problem in our country and inform about possible predictors which will help institute pre-emptive interventions to mitigate modifiable risk factors of pain after neurosurgery.
Detailed Description
Data regarding potential risk factors for postoperative pain will be collected. Preoperative factors (preoperative pain, anxiety or depression, perception about surgery, age, gender, socio-economic status, educational level, domicile location, obesity, surgical site \[infratentorial or supratentorial or cervical, thoracic or lumbar\], use of steroids and analgesics), and intraoperative factors (scalp/ESP/caudal block, incision site infiltration, dose of analgesics such as opioids, paracetamol and non-steroidal anti-inflammatory drugs (NSAIDs), co-analgesics such as nitrous oxide, gabapentionoids, dexmedetomidine, magnesium or lignocaine infusion, anti-epileptics, steroids, minimum alveolar concentration (MAC) of inhalational anesthetics, and duration of surgery and anesthesia) that are likely to be associated with occurrence of postoperative pain will be explored along with relationship between acute and persistent postoperative pain and between intraoperative nociception and postoperative pain.
Investigators
Sriganesh Kamath
Principal Investigator
National Institute of Mental Health and Neuro Sciences, India
Eligibility Criteria
Inclusion Criteria
- •all eligible consecutive consenting adult patients aged \> 18 years with preoperative Glasgow Coma Scale (GCS) score of 15 undergoing elective craniotomies and spine surgeries
Exclusion Criteria
- •children, patients with GCS \< 15, patients not extubated within 2 hours of end of anesthesia and those who not able to respond to our questions on outcomes
Outcomes
Primary Outcomes
Postoperative pain using Numerical Rating Scale
Time Frame: on days 1-3 after surgery
Acute postoperative pain
Secondary Outcomes
- patient satisfaction using Likert scale 1-5(Day 2 after surgery)
- Persistent postoperative pain using Numerical Rating Scale (NRS)(3 and 6 months after surgery)
- postoperative sleep quality using Likert 1-5 scale(Day 2 after surgery)
- duration of postoperative hospital stay in days(through hospital stay, an average of 10 days)