The impact of gum disease on the levels of a cardiovascular disease marker in the body

Not Applicable

Completed

• Conditions: Generalized periodontitis with no risk for endothelial dysfunction; Oral Health

• Registration Number: ISRCTN13626790
• Lead Sponsor: niversity of Bari Aldo Moro

Brief Summary

2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35887937/ results (added 16/01/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2019-10-10
• Study Start: 2022-07-08
• Last Update Posted: 30 January 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 140

Inclusion Criteria

1. Aged between 41 years old and 63 years old
2. Diagnosis of generalized periodontitis

Exclusion Criteria

1. Patients presenting with dental implants, orthodontic bands and ulcers
2. Patients who received periodontal treatment within 12 months prior to the start of the study
3. Patients who received systemic antibiotics within the last 6 months
4. Pregnancy or breastfeeding mothers
5. History of diabetes or a fasting glucose level greater than 126 mg/dl
6. History of cardiovascular disease
7. Patients with any systemic disease:
7.1. Diabetes mellitus
7.2. Cardiovascular disease
7.3. Kidney disease
7.4. Liver disease
7.5. Lung disease
8. Patients with cardiovascular risk factors and active smokers were excluded to minimize any confounding effect of conditions that may influence endothelial function

Study & Design

• Study Type: Interventional
• Study Design: Not specified