Assessment of duloxetine effect on post-operative pain and recovery in patients who undergo abdominal hysterectomy under general anesthesia

Phase 2

Recruiting

Conditions: postoperative pain.
Other acute postprocedural pain
G89.18

Registration Number: IRCT20120922010900N5

Lead Sponsor: Kerman University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Female

Target Recruitment: 70

Inclusion Criteria

All patients admitted to Afzalipoor Hospital for hysterectomy surgery
ASA classification of I (without systemic disease) and II (with controlled systemic disease)
informed consent of patient for participation

Exclusion Criteria

long term usage of opioids
steroid thrapy
age less than 18 and more than 85 year
pregnancy
heart, hepatic and renal failure
uncontrolled hypertension
endocrine diseases
BMI greater than 40
heart rate less than 50
evidence of heart block in ECG
presence of suizure, epilepsy and bipolar disorders
surgery lasting more than 3 hours
huge bleeding during surgery

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Postoperative pain. Timepoint: The level of pain is measured and documented every 15 minutes after patient reorientation, until discharge from recovery room. Method of measurement: Visual Analogue Scale (VAS) is used for pain assessment.

Secondary Outcome Measures

Name	Time	Method
Patient satisfaction. Timepoint: 24 hours after surgery. Method of measurement: postoperative quality of recovery (QOR) score.;Vital signs. Timepoint: every 15 minutes. Method of measurement: authomathic monitoring system.