Comparison of erythromycin and metoclopramide on gastrointestinal disorders in premature infants

Phase 3

Recruiting

• Conditions: Gastrointestinal dysmotility.; Feeding problem of newborn, unspecified; P92.9

• Registration Number: IRCT20220524054983N1
• Lead Sponsor: Karaj University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 22 January 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Neonates with gestational age of more than 32 weeks and postnatal ago of more than 2 weeks
Signs and symptoms of dysmotility; vomiting, abdominal distention, failure to defecate for more than 3 days
Absence of gastrointestinal anomaly; malrotation, intestinal atresia, necrotizing enterocolitis
Neonates with minimum weight of 800 grams and maximum of 1500 grams

Exclusion Criteria

Drug reactions
Worsening of dysmotility signs and symptoms
Positive CRP in laboratory tests or any suspicion about gastrointestinal anomalies including intestinal malrotation, necrotizing enterocolitis and intestinal atresia
The impossibility of assessing the outcome due to transfer to another center or the loss of the infant.
Dissatisfaction with participation in the study

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The improvement in clinical symptoms of dysmotility in premature neonate after a course of treatment. Timepoint: Measuring the frequency of daily feeding and lavage until the end of the treatment period. Method of measurement: Daily enteral feeding volume.