Ketamin mouthwash for Mucositus treatment
Phase 2
- Conditions
- Chemotherapy induced oral Mucositis.Oral mucositis (ulcerative) due to antineoplastic therapyK12.31
- Registration Number
- IRCT20201218049750N1
- Lead Sponsor
- Congenital pediatric Hematologic diseases
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Children above 7 years old with high grade Mucositus
Exclusion Criteria
History of psychosis,
History of seizure
History of allergy to ketamin
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mucositis grading. Timepoint: 1 hour after mouthwash rinisg, After esch day of trial. Method of measurement: Mucositis grading by examination.;Pain severity. Timepoint: 1 hour after rinsing mouthwash. At the end of each day of trial. Method of measurement: Questionnaire.;Oral Tolerance. Timepoint: 1 hour after rinsing mouthwash. At the end of each day of trial. Method of measurement: Questinnaire.;Mouthwash Onset of effect. Timepoint: 1 hour after rinsing mouthwash, at the end of each day of trial. Method of measurement: Questionnaire.;Mouthwash Duration of effect. Timepoint: 1 hour after rinsing mouthwash, at the end of each day of trial. Method of measurement: Questionnaire.
- Secondary Outcome Measures
Name Time Method