The effect of perioperative lidocaine infusion on postoperative level of serum inflammatory cytokines in patients undergoing robot-assisted laparoscopic radical prostatectomy
Not Applicable
Completed
- Conditions
- Neoplasms
- Registration Number
- KCT0006084
- Brief Summary
There are comparable in inflammatory levels between lidocaine and control groups.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Male
- Target Recruitment
- 58
Inclusion Criteria
1) Adult
2) elective robot-assisted laparoscopic radical prostatectomy
3) American Society of Anesthesiologists (ASA) physical status I or II
Exclusion Criteria
1) refusal to participate in the study
2) decision-making vulnerable being
3) history of drug side effects - allergy, arrhythmia, severe hypotension (mean blood pressure <60 mmHg), severe bradycardia (<40beats/min)
4) Hemorrhage that urgently required packed red blood cells - hemoglobin <7 g/dL
5) History of vascular disease
6) History of pulmonary disease
7) History of cardiac disease
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method measurement of serum cytokines (interleukin-6, interleukin-10, interleukin-17, tumor necrosis factor-alpha, ??? interferon-gamma)
- Secondary Outcome Measures
Name Time Method Biochemical recurrence of prostate cancer;Clinical patient recovery - pain, length of stay, Clavien-Dido classification;Experimental drug-related complications