The Effect of L-Carnitine on the Prevention of Contrast Induced Nephropathy in Patients Undergoing Coronary Angiography in Heshmat Hospital in 2017
Phase 3
- Conditions
- Cardiac patients are candidates for angiography.Atherosclerotic heart disease of native coronary artery
- Registration Number
- IRCT20180921041079N1
- Lead Sponsor
- Rasht University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 143
Inclusion Criteria
All patients who Undergo Elective Angiography and PCI After Approval of the Plan in 1396 Will be Located at Rasht Medical Center.
Patient Satisfaction: The Willingness to Participate in the Study and Sampling
Exclusion Criteria
ST elevation MI
Pregnancy
History of CABG in the last 6 months
History of PCI in the last 6 months
Cardiogenic shock
Simultaneous use of nephrotoxic drugs
Recent exposure to contrast material (from 2 days before 2 days later)
Renal transplantation biography
Thyroid disorders
Corticosteroids
LVEF<35%
Patients who have not received full doses of medication after entering the study due to Digestive complications or incompleteness of the drug will be excluded from the study.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Contrast Nephropathy. Timepoint: L carnitine is given 24 hours before coronary angiography and then every 8 hours. Method of measurement: Serum creatinine, Glomerular filtration degree, Echocardiography.
- Secondary Outcome Measures
Name Time Method