Acute Stress Response to Non-Severe Burn Injuries

Not Applicable

• Conditions: Burn Injuries; Injuries and Accidents - Burns

• Registration Number: ACTRN12621001550897
• Lead Sponsor: Murdoch University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-11-15
• Last Update Posted: 22 November 2021

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 82

Inclusion Criteria

Less than or equal to 20% total body surface area burn injury
Expected to undergo at least one surgery during their inpatient admission for a burn injury

Exclusion Criteria

Facial burns (if unable to form a seal around the mouthpiece for the metabolic assessment)
Patients on continuous naso-gastric feeding

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Metabolic flexibility - determined by changes observed in respiratory exchange ratio (RER) as measured by sampling of expired gas using indirect calorimetry, post-consumption of the standardized high carbohydrate meal in the form of a 300ml glucose drink containing 75g of glucose.[RER will be measured for a continuous 60 minute period following the consumption of the standardised high carbohydrate meal at each assessment.<br><br>Baseline assessment: ~48 hours pre surgery<br>2nd assessment: 48-72 hours post surgery<br>3rd assessment: 6 weeks post surgery<br>4th assessment 12 month post surgery]